《植物生理学报》 2017, 53(7): 1159-1170

胞间连丝——植物细胞间交流的纳米通道

段茜茜, 王冬梅^*

河北农业大学生命科学学院, 河北省植物生理与分子病理学重点实验室, 河北保定071001

通信作者：王冬梅；E-mail: dongmeiwang63@126.com

摘　要：

有效的细胞间交流对单细胞生物和多细胞生物的生存至关重要。因为植物细胞被包裹在坚硬的细胞壁内, 细胞质内容物的直接胞间交流只能通过胞间连丝, 一种连接相邻细胞胞质的膜内衬纳米通道来实现。研究表明, 这种膜内衬胞间通道在动物中有与之相似的通道纳米管。它们都能促进各种形式的大分子的交流, 同时也使一些病原物利用这些通道从一个宿主细胞移动到另一个细胞。然而, 宿主免疫监督系统也已经进化出了多种策略去防止病原物对其利用。最近的一些研究表明, 胞间连丝在植物的先天免疫反应中扮演着重要角色, 通过此种监督机制把胞间连丝与免疫信号转导通路融为一体。本文主要讨论胞间连丝在细胞间物质交流过程中的调控机制。

关键词：胞间连丝; 通道纳米管; 细胞间交流; 病原物; 免疫信号转导通路

收稿：2017-02-07   修定：2017-06-27

资助：国家自然科学基金(30971706和31471421)、河北省自然科学基金(C2008000321)和“973”计划前期研究专项(2014CB160318）。

Plasmodesmata—the nanotubes for intercellular communication of plants

DUAN Xi-Xi, WANG Dong-Mei^*

Key Laboratory of Hebei Province for Molecular Plant-Microbe Interaction, College of Life Sciences, Agricultural University of Hebei, Baoding, Hebei 071001, China

Corresponding author: WANG Dong-Mei; E-mail: dongmeiwang63@126.com

Abstract:

Effective intercellular communication is critical for the survival of both unicellular and multicellular organisms. Because plant cells are encased in rigid cell walls, direct cell-to-cell exchange of cytoplasmic content is only possible through plasmodesmata, membrane-lined nanotubes that connect the cytoplasm of adjacent cells. Studies have shown that such membrane-lined intercellular channels have some similar channels which called tunneling nanotubes in animals. They all facilitate the exchange of various forms of macromolecules, but at the same time make some microbial pathogens to exploit those channels to move from one host cell to another. However, host immune surveillance system may have also evolved strategies to offset such exploitation of them by the pathogen. Some recent discoveries suggest that cellular connectivity via plasmodesmata plays an important role in innate immune responses, and plants integrated plasmodesmata into immune signaling pathways through the supervision mechanism. In this article, the regulation mechanism of plasmodesmata in intercellular communication were discussed.

Key words: plasmodesmata; tunneling nanotubes; intercellular communication; pathogens; immune signaling pathways